SOUTH BEND, Indiana -- No. 10-ranked USC sustained its first loss of the season in a one-sided 48-20 win by No. 21 Notre Dame, as Trojans quarterback Caleb Williams had his first multi-interception game in his two years with the program, throwing 3 picks

USC also lost a fumble late and allowed a 99-yard kickoff return for touchdown to undercut any comeback hopes.

Full postgame coverage to come.

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